Tec-Control Chromatography Systems

Tec-Control Chromatography Systems
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OverviewSolventsManualsModels and Ordering

Overview

For radiopharmaceutical quality control

Tec-Control Chromatography tests the radiochemical purity of specific Tc-99m-labeled radiopharmaceuticals. The accompanying chart shows which strips and solvents are required to perform each individual test. Some solvents must be purchased separately (see Sigma-Aldrich chart) due to hazardous material shipping restrictions.

Detailed instruction manuals are packaged with each strip container, although our Radiopharmaceutical QC Procedure Manual (151-000) explains paper chromatography in greater detail.

 

References:

Miniaturized Chromatographic Quality-Control Procedures for Tc-99m Radiopharmaceuticals; A. Michael Zimmer and Dan G. Pavel, Journal of Nuclear Medicine, Vol. 18/12, Dec. 1977, pg. 1230.

Technical Parameters Associated with Miniaturized Chromatography Systems; Raimund A. Taukulis, A. Michael Zimmer, Dan G. Pavel and Bhupendra A. Patel, University of Illinois Medical Center, Chicago, Illinois, Journal of Nuclear Medicine Technology, Vol. 7/1. 


Solvents

RADIOPHARMACEUTICAL  SOLVENT(S) REQUIRED*  STRIPS REQUIRED 
 Aluminum Breakthru  150-781 10 µg/ml  150-782  
 Aluminum Breakthru  150-783 5 µg/ml  150-782 
 Bicisate (Neurolite™)  Ethyl Acetate 99.%  150-130 
 Diphosphonate  Acetone (HPLC Grade), Distilled H2O  150-001 & 150-005 
 Disofenin (Hepatolite™)  150-160, Distilled H2O  150-122 & 150-125 
 DMSA  Acetone (HPLC Grade),  150-025 
 DTPA  Acetone (HPLC Grade), Distilled H2O  150-001 & 150-005 
 Exametazine (Ceretec™)  Ethyl Acetate 99.% 
150-130 
 Fluorodeoxyglucose (FDG)
Acetone (HPLC Grade) 150-127
 Glucoheptonate  Acetone (HPLC Grade), Distilled H2O  150-001 & 150-005 
 HDP  Acetone (HPLC Grade), Distilled H2O  150-001 & 150-005 
 MAA  Acetone (HPLC Grade),  150-001 
 MAG3 (Mertiatide™)  Acetone, (HPLC Grade),
Chloroform 99.8%
Tetrahydrofuran 99+% 
150-951 & 150-952 
 MDP  Acetone (HPLC Grade), Distilled H2O  150-001 & 150-005 
 Mebrofenin (Cholotec™)  150-160, Distilled H2O  150-122 & 150-125 
 Pyrophosphate  Acetone (HPLC Grade), Distilled H2O  150-001 & 150-005 
 Sestamibi (Cardiolite™ and  
 Miraluma™) 
Ethyl Acetate 99.%  150-991 
 Sulphur Colloid  Acetone (HPLC Grade)  150-001 
 Tc-99m (reduced)  Acetone (HPLC Grade),  150-001  
 Tc-99m Monoclonal  Antibodies  0.9% Saline  150-771
 Tetrofosmin (Myoview™)  Ethyl Acetate 99.% 
150-971 
 In-111 Octreotide
 (Octreoscan™) 
150-773 & 0.9% Saline  150-771 **
 In-111 Monoclonal
 Antibodies 
150-773 & 0.9% Saline  150-771 ** 
 In-111/Y-90 Zevalin™  0.9% Saline  150-772 
 I-131 Monoclonal Antibodies
 And Neutrospec™ 
0.9% Saline  150-771 

* See Sigma-Aldrich product matrix for solvents.
** Note: A Well Plate is suggested to perform QC on these radiopharmaceuticals
Contact Fisher Scientific Corp. 800-766-7000 / www.fishersci.com / Item #14-245-71

Manuals

Models and Ordering

To order, call 1-800-224-6339

Chromatography Strips

150-001   Strips, RED, 50/pkg   $38.00
150-005   Strips, BLACK, 50/pkg  48.00
150-025   Strips, YELLOW, 50/pkg  60.00
150-122   Strips, ORANGE, 50/pkg  48.00
150-125   Strips, LIGHT BLUE, 50/pkg   48.00
150-127
 Strips, GREEN, 50/pkg
 48.00
150-130   Strips, GOLD, 50/pkg  56.00
150-771   Strips, DARK GREEN, 50/pkg   51.00
150-772   Strips, BLUE, 50/pkg   51.00
150-951   Strips, LIME, 50/pkg  50.00
150-952   Strips, PEACH, 50/pkg   50.00
150-971   Strips, TEAL, 50/pkg  57.00
150-991   Strips, PINK, 50/pkg   57.00
150-782   Strips, ALUMINUM, 50/pkg   40.00

Chromatography Solvents

150-160  Solvent, 20% Sodium Chloride, 30 ml   $30.00
150-773
Solvent, DTPA, 5 ml  30.00
150-781 Solvent, Aluminum Standard, 5 ml, 10 µg/ml  40.00
150-783  Solvent, Aluminum Standard, 5 ml, 5 µg/ml  40.00

Related Items: 

150-960 Developing Vials, 10 ml, 288/case
(used for all Tec-Control testing) 
$285.00
150-961  Developing Vials, 5 ml, 144/case
(used for Sestamibi & Tetrofosmin) 
125.00
066-533  Forceps, Curved, Locking, 9.5" l
(24.1 cm) 
38.00
066-535  Forceps, Straight, Locking, 9.5" l
(24.1 cm) 
38.00
066-536  Forceps, Curved, Non-Locking,
12.5" l (31.7 cm) 
68.00
Tec-Control Solvent Vendor:
Sigma-Aldrich Chemical Company
800-558-9160 / www.sigmaaldrich.com

Note: Customers outside the US should visit Sigma-Aldrich web site to locate a regional office.

Solvent Description Vendor Part #
Acetone HPLC Grade 27072-5
Ethyl Acetate 99.5% ACS Reagent 31990-2
Chloroform 99.8% ACS Reagent  31998-8
Tetrahydrofuran 99+% ACS Reagent  36058-9

Request More Information
Conditions of Purchase 

Biodex, Inc.

1-800-224-6339
Int'l +1-631-924-9000